Teva Pharmaceuticals Biocatalytic Process Designer in Debrecen, Hungary

Biocatalytic Process Designer

Date: Dec 7, 2018

Location: Debrecen, HU, 4042

Company: Teva Pharmaceutical Industries Ltd.

Company Info

Teva is a global pharmaceutical leader and the world’s largest generic medicines producer, committed to improving health and increasing access to quality health solutions worldwide. Our employees are at the core of our success, with colleagues in over 80 countries delivering the world’s largest medicine cabinet to 200 million people every day. We offer a uniquely diverse portfolio of products and solutions for patients and we’ve built a promising pipeline centered around our core therapeutic areas. We are continually developing patient-centric solutions and significantly growing both our generic and specialty medicines business through investment in research and development, marketing, business development and innovation. This is how we improve health and enable people to live better, healthier lives. Join us on our journey of growth!

Job Description

  • Exploring routes of synthesis for relevant API based on patent and scientific literature, including both synthetic and biocatalytic options

  • Design of routes of synthesis including biocatalytic steps for the preparation of API or intermediates

  • Selection and recommendation of enzymes for given biocatalytic steps based on literature, databases, commercial sources and structural information

  • Following the scientific and patent literature related to running biocatalytic developments and biocatalytic technologies in general

  • Recommendation for the biocatalytic process development teams with regards to the reaction conditions and technologies to be explored

  • Preparation of cost calculations for biocatalytic routes

  • Cooperation with project managers and colleagues from other R&D sites, in English

Qualifications

  • At least Master of Science level university degree in chemistry, chemical engineering or pharmacy

  • Proficiency and experience in biocatalysis or enzyme chemistry

  • High level knowledge in organic chemistry

  • Creativity, susceptibility for new methods, technologies in the field of biocatalysis

  • Good communication skills in English

  • User level computer skills

  • Advantages:

  • Qualification related to enzyme chemistry

  • Ph.D. degree obtained in biocatalysis, enzyme chemistry, biochemistry or related areas

  • Proficiency in enzyme immobilization, use of immobilized enzyme preparations or enzyme kinetic measurements

  • Proficiency in computational modelling of enzymes (docking, molecular dynamics)

EOE including disability/veteran