Pfizer Senior Scientist, Protein Crystallography in Cambridge, Massachusetts
We are seeking a protein crystallography expert who will be involved in crystal structure determination of industry-leading biotherapeutics as part of Pfizer's BioMedicine Design team in Cambridge, MA. The successful candidate will join project teams in multiple therapeutic areas to assist structure-based optimization of protein therapeutic leads in early through late discovery.
Works with project teams as a primary source of structure knowledge of protein antigens and of their binding complexes with protein biotherapeutic leads. Effectively presents/communicates results of structure analysis and recommendations to colleagues with diverse scientific backgrounds. Implements new or improved crystallography software packages to increase throughput and accuracy of structure determination workflows.
PhD in biochemistry, chemistry, or a related field and 0-1 years of experience in the biopharmaceutical industry.
Experience in guiding crystallography projects from start to finish.
Expertise in commonly used protein crystallography software packages.
Use of molecular visualization software packages to produce high-quality 3D images of biological macromolecules.
Working knowledge of antibody structure and function is a significant advantage.
Working knowledge of crystallization robotics is desirable.
Knowledge in optimization of crystallization conditions to produce diffraction-quality crystals.
Conducting research projects in a team setting, presenting results to scientists of varying technical backgrounds.
Knowledge in computational scripting is an advantage.
Good track record of publication in topics involving protein structure determination and analysis.
EEO & Employment Eligibility
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Other Job Details:
Last Date to Apply for Job: January 11, 2019
Eligible for Relocation Package
Eligible for Employee Referral Bonus
Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.