Gilead Sciences, Inc. Principal Research Scientist Novel T Cell Therapies in Amsterdam, Netherlands

For Current Kite Pharma Employees and Contractors:

Please log onto your Internal Career Site to apply for this job

Job Description

Kite is a bio-pharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors.

Kite Europe is currently adding additional talent as it focuses on developing the European Region in support of providing maximum access to patients with unmet needs. We’re building a state-of-the art manufacturing site in the Netherlands (Amsterdam-Hoofddorp).

We’re currently seeking to recruit highly motivated talents for different positions, to join us and be part of our exciting journey in the development of innovative cancer immunotherapies and their translation to the treatment of patients with cancer.

Department description

For our Amsterdam based research facility, we are seeking a highly motivated Principal Research Scientist with expertise and a track record in T cell engineering/T cell immunology to join our ambitious team. You will assume a key scientific role by contributing to the design and execution of our scientific projects. The successful candidate will manage a small, multicultural scientific team and actively engage in experimental work. The Principal Research Scientist will plan and execute laboratory studies, organize and analyze results and communicate and present findings in team meetings. As a Principal Research Scientist you will fulfil a key role within the research team and will be involved in different activities with a high level of variety and a significant level of responsibility.

Your responsibilities

Your responsibilities, among others, will be:

  • Designing laboratory experiments to develop novel approaches to target cancer with engineered T cells. Examples include, but are not limited to, strategies to efficiently identify neo-antigen reactive T cells, the identification and non-clinical evaluation of therapeutic TCR candidates and the in vitro and in vivo assessment of engineering strategies to enhance the therapeutic potency of TCR-modified T cells

  • Supervise the work of a small research team including but not limited to organizing and prioritizing laboratory work according to timelines and review of generated experimental results;

  • Hands-on execution of laboratory work alongside the team;

  • Analyze and present scientific results to diverse audiences;

  • Document experimental results to enable clinical studies and patent applications;

  • Work with cross-functional international teams to advance the development of T cell therapies including those targeting tumor neo-antigens

  • Other duties as assigned

Challenges of the role

  • The opportunity to join a growing company with promising results in the field of innovative cancer immunotherapies

  • A unique position in a field which is becoming highly competitive

  • Be part of a passionate and talented team

Your profile

Education

  • PhD degree with subsequent postdoctoral training and preferably industry experience in T cell engineering/T cell immunology

Knowledge/experience

  • Evidence of a successful academic or industry track-record (for example lead authorships on publications and/or being a named inventor on patent applications).

  • Further expertise in one or multiple of the following areas is highly advantageous: tumor neo-antigen biology, CD4+ T cell immunobiology, genetic screenings, e.g. using CRISPR and RNAi, next-generation single cell PCR methods (e.g. Droplet-based PCR methods), in vivo models to study T cell immunity and process development to detect and isolate antigen-specific T cells

  • Familiarity with immunological techniques applied to study T cell biology and develop T cell therapies, including but not limited to isolation, in vitro cultivation and phenotypic characterization of primary human immune cells, genetic manipulation of primary immune cells and cell lines using various transduction systems and multi-color flow cytometry

  • Ability to translate scientific ideas into comprehensive experiments aiming to develop broadly applicable, industrial-scale T cell therapies

  • Strong organizational and record keeping skills

  • Proactive, self-motivated team player with strong interpersonal skills, appropriate sense of urgency and the ability to work independently

  • Excellent interpersonal, verbal and written communication skills are essential in this collaborative work environment

  • Comfortable in a fast-paced growing company environment with minimal direction and able to adjust workload based upon changing priorities

If you have the ability to thrive in a dynamic and fast-paced environment and feel that the moment has come for you to be part of such an exciting journey towards eliminating the burden of chronic cancer care, don’t miss out on this opportunity to join us.

More information?

Would you like to know more before you apply? Please contact Heidi Kroon - talent acquisition specialist, via: CareersEU@kitepharma.com .

Recruitment agencies: We seldom make use of agencies, and when we do, we have a PSL in place. We would appreciate if you did not contact hiring managers or the recruitment team directly, since we will not be able to respond to you.

#LI-HK1

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com . Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma .

Equal Employment Opportunity (EEO)

It is the policy of Gilead Sciences, Inc. and its subsidiaries and affiliates (collectively "Gilead" or the "Company") to recruit select and employ the most qualified persons available for positions throughout the Company. Except if otherwise provided by applicable law, all employment actions relating to issues such as compensation, benefits, transfers, layoffs, returns from layoffs, company-sponsored training, education assistance, social and recreational programs are administered on a non-discriminatory basis (i.e. without regard to protected characteristics or prohibited grounds, which may include an individual’s gender, race, color, national origin, ancestry, religion, creed, physical or mental disability, marital status, sexual orientation, medical condition, veteran status, and age, unless such protection is prohibited by federal, state, municipal, provincial, local or other applicable laws). Gilead also prohibits discrimination based on any other characteristics protected by applicable laws.

For Current Kite Pharma Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

Gilead Sciences, Inc. is a research-based biopharmaceutical company that discovers, develops and commercialises innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

If this is not the right move for you now but remain interested in a career at Gilead Sciences please connect with us via our talent community at http://gilead.avature.net/Gilead